Chlormadinone Acetate email@example.com
|Posted on:||31 January 2018 / 07:24|
CAS NO.: 302-22-7
Molecular Formula: C23H29ClO4
Chemical Properties: White Crystalline Solid
Usage: Potent progesterone,Orally active progesteron with antiandrogenic activity; has been used in combinations as an oral contraceptive. Progestogen; antineoplastic (hormonal).
Delivery: Express courier.
Chlormadinone acetate (CMA) is a derivative of naturally secreted progesterone that shows high affinity
and activity at the progesterone receptor. It has an anti-estrogenic effect and, in contrast to natural progesterone, shows moderate anti-androgenic properties. CMA acts by blocking androgen receptors in
target organs andby reducing the activity of skin 5alpha-reductase. It suppresses gonadotropin secretion
and thereby reduces ovarian and adrenal androgen production. CMA shows high contraceptive efficacy by inhibiting ovulation due to its ability to suppress or disrupt endogenous gonadotropin secretion and,
by this, inhibits follicular growth and maturation. In addition, it suppresses endometrial thickness
and increases the viscosity of cervical mucus.
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