|Posted on:||3 February 2018 / 09:19|
Appearance:The product is white or almost white crystalline powder. Dissolved in glacial acetic acid , slightly soluble in ethanol , slightly soluble in chloroform or water , very slightly soluble in acetone
Minoxidil is a clinical oral medication for lowering blood pressure , also known as minoxidil , piperazine pyrimidine diamine, buck fixed , Minoxidil blood given , are potassium channel opener , can direct relaxation of vascular smooth muscle, there is a strong expansion of the role of small arteries , the peripheral resistance decreased , blood vessels expand, blood pressure , and had no effect on the capacitance vessels , it can promote venous return . Meanwhile, the reflex regulation and positive
frequency effect, can increase cardiac output and heart rate , but does not cause orthostatic hypotension. Clinic for refractory hypertension and renal hypertension treatment. Can also be used for other antihypertensive drugs ineffective severe hypertension , but the need to avoid sodium retention diuretics can be combined to make increased efficacy , adverse reactions decreased.
Minoxidil, applied topically, is widely used for the treatment of hair loss. It is effective in helping promote hair growth in both males and females with androgenic alopecia. About 40% of men experience hair regrowth after 3-6 months. Minoxidil must be used indefinitely for continued support of existing hair follicles and the maintenance of any experienced hair regrowth. ]It is the only topical product that is
FDA approved for androgenic hair loss. Treatments usually include a 5% concentration solution that is designed for men, and a 2% concentration solution for women.
Minoxidil needs to be applied twice daily, and may be used indefinitely for continued support of existing hair follicles and the maintenance of any experienced hair regrowth. To achieve maximum effect, the
solution should be in contact with the scalp for at least 4 hours before allowing hair to get wet.
Minoxidil stimulates hair follicles and growth, but does not reduce dihydrotestosterone (DHT) or the
enzyme responsible for its accumulation around the hair follicle, 5-alpha reductase, which is the primary mediator of male pattern baldness in genetically susceptible individuals. Therefore, when treatment is stopped, the DHT has its expected effect of shrinking and ultimately destroying the genetically
predisposed hair follicles. There are multiple types of minoxidil applications: dropper, foam and spray.
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